Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Objectives: To compare observer agreement between endodontists and oral and maxillofacial radiologists (OMRs) in the detection and measurement of periapical lesions as depicted in cone beam computed tomography with 2 voxel sizes.Study Design: In total, 256 CBCT images of maxillary molars were evaluated by 2 endodontists and 2 OMRs. Images were obtained at 0.2 mm and 0.4 mm voxel sizes. Observers evaluated 64 non-endodontically and 64 endodontically treated teeth for the presence of periapical lesions using a 5-point confidence scale.

Objectives. To evaluate the outcome of secondary alveolar bone grafting (SABG) in patients with cleft lip and palate (CLP) at 16 years of age, and to identify predictors associated with surgical failure.Study Design. This retrospective follow-up included 91 patients with 100 cleft palates treated with SABG at a mean age of 9.2 years. Analyzed possible predictors for surgical failure were gender, dental development stadium, type of cleft, side, tooth erupting into the graft, cortical boundary, presence of a lateral incisor, extraction, preoperative expansion, oral hygiene, retention device and age.

Oral squamous cell carcinoma (OSCC) accounts for approximately 90% of all oral cancers and is among the most common malignant tumors worldwide.1 Treatment options for OSCC include single-modality therapy of surgery, radiotherapy, or various combinations of these modalities with or without systemic chemotherapy.2 Although recent advances in the treatment and diagnostic techniques for oral cancer have significantly improved patient outcomes, the highly metastatic potential and high rate of resistance development to chemotherapy and radiotherapy are the major issues that remain unsolved.

Delayed-onset infection is defined as infectious swelling and trismus accompanied by pain or the presence of suppuration starting approximately 30 days after surgery. This study aimed to describe the occurrence and potential predisposing factors of delayed-onset infection.

The study aimed to evaluate the clinical characteristics and outcomes of patients with metastatic tumors in the oral region.

Head and neck mucosal melanoma (HNMM) is a rare disease with a poor prognosis. The aim of this research was to analyze clinical characteristics and prognostic factors in a Latin-American cohort.

The pathogenesis of oral cancer is a complex and multifactorial process that requires a deep understanding of the underlying mechanisms that are involved in the development and progress of malignancy. The ever-improving comprehension of the diverse molecular characteristics of cancer, the genetic and epigenetic alterations of tumor cells, as well as the complex signaling pathways that are activated and frequently crosstalk, open up promising horizons for the discovery and application of diagnostic molecular markers, and set the basis for an era of individualized management of the molecular defects underlying and governing oral premalignancy and cancer.

The purpose of this study was to assess apparent diffusion coefficient (ADC) values associated with MRONJ at each stage of the disease compared to controls.

: To evaluate the impact of orthognathic surgery on the quality of life, and to compare single and double-jaw surgeries in terms of ratio and patient's perception about the postoperative period.

This study investigated the association of computed tomography (CT)-verified degenerative condylar changes with disk displacement (DD) and gender.

I am delighted to introduce Antonia (Toni) Kolokythas, DDS, MSc, MSed, FACS, as the new Oral Surgery Section Editor for Triple O. Dr. Kolokythas is currently the Department Head and Program Director of Oral and Maxillofacial Surgery at the University of Rochester. After earning a dental degree at the University of Thessaloniki in Greece, she completed her residency training in Oral and Maxillofacial Surgery at the University of Illinois at Chicago (UIC), followed by two surgical fellowships in Head and Neck-Maxillofacial Oncology and Reconstruction at the University of Maryland at Baltimore and the University of California at San Francisco.

A 60-year-old male came to the oral medicine clinic to evaluate his non-healing oral sores, which had persisted for 12 months. He complained of painful tongue ulcers that affected his ability to eat and contributed to a 35-pound weight loss over the last 5 months. The patient reported fatigue in the last 3 months, accompanied by a 5-week history of skin abnormalities. He also had a brief history of a scrotal lesion in the past. The patient had been evaluated and treated by multiple providers throughout the past year without positive outcomes.

To assess the effects of eye coverage on anxiety in candidates for surgical removal of impacted third molars.

Adenoid cystic carcinoma (AdCC) is a rare, indolent salivary gland tumor that is reported to be driven by fusion genes. However, MYB/MYBL1-NFIB fusions have been detected in only <60% of all AdCC cases and the oncogenic driver mutations in approximately 40% of AdCC remain unknown. Our aim was to identify novel gene fusions in AdCC.

Oral hairy leukoplakia (OHL) is a benign Epstein-Barr virus infection typically presenting as a white lesion on the lateral border of the tongue. Historically, OHL was described in patients who are severely immunocompromised, such as those with HIV-AIDS and organ transplantation patients. OHL is increasingly seen in patients who are not severely immunocompromised. This study reviews forty-five cases of OHL in a single institution and characterizes the clinical features of these relatively immunocompetent patients.

The objective was to assess the effects of object position, field of view (FOV) size, kVp, and a metal artifact reduction (MAR) algorithm on metal artifacts in CBCT as measured with an auto-edge counting method.

A 50-year-old Latin American female patient complained of a painful lesion in the hard palate on a telephone consultation. The patient was isolated at home after receiving the diagnosis of coronavirus disease 19 (COVID-19), confirmed by the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA via polymerase chain reaction. The diagnosis was made approximately 8 days before the consultation. The only symptom related to COVID-19 was a persistent headache for 3 days, and no other medication was prescribed besides nonopioid analgesics.

Xeroderma pigmentosum (XP) is a rare inherited disease caused by deficiencies in DNA damage repair, which mainly results from the failure of nucleotide excision repair or defects in translesion DNA synthesis. The development of multiple malignancies is one of the most prominent features of this condition, which is clinically characterized by the occurrence of hyperpigmentation and lesions associated with sunlight exposure. Lip squamous cell carcinoma (SCC) in patients with XP has rarely been reported, and information regarding the genetic analysis of these patients is limited.

: This systematic review (SR) assessed the radiographic extent of Maxillofacial Gorham's Disease (MGD) and its impact on recurrence.

Idiopathic pulmonary fibrosis (IPF) patients commonly present with sicca symptoms. This study aims to assess labial minor salivary glands (LMSG) in those patients to rule out Sjögren's syndrome (SS), in which sicca symptoms are the clinical hallmark.

: To evaluate the immunoexpression profiles of breast cancer 1 (BRCA1) and acetyl-histone H3 (AcH3) in squamous cell carcinoma of the mobile tongue (SCC-MT) and their correlation with epidemiological data and the histopathological grade of tumors.

: To develop the first edition of a Chinese evidence-based position paper on the management of oral leukoplakia (OLK).

The current study was designed to investigate the correlation between the bony morphology of the mandibular condyle and the occurrence of TMJ idiopathic anterior dislocation.

The aims of this pilot investigation were to calculate the levels of sensitivity and specificity of salivary glands ultrasonography (SGUS) in diagnosing Sjögren syndrome (SS) and to assess the ultrasonographic findings of parotid and submandibular glands.

The purpose of this study was to determine the prevalence of throat pain and otalgia as presenting symptoms in patients with oropharyngeal squamous cell carcinoma (OPSCC) stratified by the cancer being their first or recurrent/second primary head and neck cancer (fHNC or rsHNC).

Third molar surgery is the most common ambulatory procedure done by oral and maxillofacial surgeons. Surgical approaches for the removal of third molars have been published since the 20th century. This paper reviews the history and development of extraction techniques through a literature review. The literature was selected through a search of electronic database. Key words for the Medline search were mandibular/maxillary third molar, impacted mandibular/maxillary third molar, mandibular/maxillary third molar flap design, mandibular/maxillary third molar incision.

The aim of this systematic review was to describe the quality of life and oral health–related quality of life of patients affected by medication-related osteonecrosis of the jaw.

To explore the usefulness of magnetic resonance neurography (MRN) in the diagnosis and management of trigeminal neuralgia (TN).

: The aim of this study was to analyse the thrombophilia population that underwent oral and/or maxillofacial surgery at our centre.

This study aimed to evaluate the expression of CMTM6 and PD-1/PD-L1 in oral squamous cell carcinoma (OSCC), and to further explore its clinical significance in OSCC.

Recurrent disease occurs in a significant proportion of early-stage oral squamous cell carcinoma (OSCC) despite removal of the entire tumor with clear surgical margins. Our study seeks to identify clinicopathologic factors that increase the risk of locoregional recurrence in for T1N0 OSCC.

A nine-year-old boy was admitted to the pediatric unit of Hospital das Clínicas of Universidade Federal de Minas Gerais for diagnostic investigation. The patient had consanguineous parents and two healthy siblings (8 and 25 years old). His family medical history revealed that the father and an aunt were affected by cutaneous psoriasis.

Odontogenic keratocysts (OKC) are a commonly occurring, benign cystic intraossesous lesion, thought to arise from the cell rests of the dental lamina. Most instances of OKC are commonly found in the posterior aspect of the mandible.In rare instances there have been reported cases of OKCs arising in the peripheral gingiva, but these cases are few and far between.Rarer still are the few documented cases of OKCs arising in other soft tissues of the mouth. There are many divided opinions on the diagnosis of these lesions and whether they are truly odontogenic in origin given their location when they are enucleated from a soft tissue area.

: The aim of this study is to present a systematic review of the effectiveness of discopexy in managing internal derangement of the temporomandibular joint (TMJ).

The purpose of the present study was to investigate the effect of acupuncture on xerostomia in irradiated patients with head and neck squamous cell carcinoma (HNSCC).

To evaluate the efficacy of maxillomandibular advancement (MMA) surgery for the treatment of malocclusion and obstructive sleep apnea (OSA) in an adolescent population.

This cross-sectional study established the relationships between temporomandibular disorder (TMD) symptoms, psychological well-being (PWB), and psychological distress (PD). Additionally, the psychological predictors for various TMD features were determined.

The aim of this study was to investigate whether the medial angulation of the styloid process (SP), regardless of its length, has an association with self-reported symptoms of Eagle's syndrome.

This study aimed to assess mandibular morphological changes to the condyle, ramus, mandibular body, and inferior mandibular border defect after sagittal split ramus osteotomy in class II and III patients.

Juvenile idiopathic arthritis (JIA) is the most common chronic pediatric rheumatologic condition.1 The etiology and pathogenesis of JIA are unknown, although a variety of environmental and immunogenic factors may contribute to the disease.2 JIA is diagnosed through the history and clinical presentation, as well as radiologic abnormalities.3 In general, symptoms begin before the 16th birthday and persist for at least 6 weeks.3 JIA affects at least 300,000 children in the United States; approximately 40% of those have diagnosed temporomandibular joint (TMJ) involvement.

. We propose a new topical radiographic contrast method for distinguishing non-cavitated from cavitated radiolucencies. Laboratory tests and a pilot clinical trial were designed to test the feasibility and efficacy of the method.

Bilateral sagittal split osteotomy (BSSO) is one of the most frequently used treatments for jaw deformity worldwide. However, lower lip hypoesthesia is a postoperative complication of BSSO. Trigeminal somatosensory evoked potential can be used to evaluate neural pathway abnormalities by measuring latency. The purposes of this study were to measure latency before and after BSSO and to examine the relationship between latency and the duration of hypoesthesia recovery.

In the present study, we sought to investigate the in vivo musculoaponeurotic architecture of the masseter muscle (MM) volumetrically with ultrasound in asymptomatic participants. It was hypothesized that the mean fiber bundle length (FBL) and mean aponeurotic height of laminae of the MM differ significantly between the relaxed state and maximally contracted state upon elevation of the mandible.

This study aimed to investigate the expression of phosphofructose kinase-2/fructose-2, 6-biophosphatase 3 (PFKFB3) and its association with lymphangiogenesis in oral squamous cell carcinoma (OSCC).

Pemphigus vegetans is a rare variant of pemphigus vulgaris. Here, we report a rare case of post-parturition pemphigus vegetans in a young woman without any prior medical history. The patient presented with extensive oral mucosal erosion, conjunctivitis, and fingernail dystrophy. A histopathological biopsy taken from the tongue showed pseudoepitheliomatous hyperplasia of the epidermis with eosinophilic spongiosis, and an intraepidermal cleft and direct immunofluorescence showed intercellular IgG and C3 deposition.