Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

A nine-year-old boy was admitted to the pediatric unit of Hospital das Clínicas of Universidade Federal de Minas Gerais for diagnostic investigation. The patient had consanguineous parents and two healthy siblings (8 and 25 years old). His family medical history revealed that the father and an aunt were affected by cutaneous psoriasis.

: The aim of this study is to present a systematic review of the effectiveness of discopexy in managing internal derangement of the temporomandibular joint (TMJ).

Odontogenic keratocysts (OKC) are a commonly occurring, benign cystic intraossesous lesion, thought to arise from the cell rests of the dental lamina. Most instances of OKC are commonly found in the posterior aspect of the mandible.In rare instances there have been reported cases of OKCs arising in the peripheral gingiva, but these cases are few and far between.Rarer still are the few documented cases of OKCs arising in other soft tissues of the mouth. There are many divided opinions on the diagnosis of these lesions and whether they are truly odontogenic in origin given their location when they are enucleated from a soft tissue area.

: The purpose of the current study was to investigate the effect of acupuncture on xerostomia in irradiated head and neck squamous cell carcinoma (HNSCC) patients.

This study aimed to assess mandibular morphological changes to the condyle, ramus, mandibular body, and inferior mandibular border defect after sagittal split ramus osteotomy in class II and III patients.

To evaluate the efficacy of maxillomandibular advancement (MMA) surgery for the treatment of malocclusion and obstructive sleep apnea (OSA) in an adolescent population

. This cross-sectional study established the relationships between TMD symptoms, psychological well-being (PWB), and psychological distress (PD). Additionally, the psychological predictors for various TMD features were determined.

To investigate whether the medial angulation of the styloid process (SP), regardless of its length, has an association with self-reported symptoms of Eagle's syndrome.

. We propose a new topical radiographic contrast method for distinguishing non-cavitated from cavitated radiolucencies. Laboratory tests and a pilot clinical trial were designed to test the feasibility and efficacy of the method.

Objective: The objective of this report is to review the current available clinical trials of JIA regarding the diagnosis, management, or outcomes of TMJ involvement. We hypothesized that such clinical trials are rare.Study Design: The Clinical Trials Database was queried through ClinicalTrials.gov for keywords relevant to juvenile idiopathic arthritis and temporomandibular joint. The outcome variables were: clinical trial number, principal investigator information, trial information, and reported results.

Bilateral sagittal split osteotomy (BSSO) is one of the most frequently used treatments for jaw deformity worldwide. However, lower lip hypoesthesia is a postoperative complication of BSSO. Trigeminal somatosensory evoked potential (TSEP) can be used to evaluate neural pathway abnormalities by measuring latency. The purposes of this study were to measure latency before and after BSSO and to examine the relationship between latency and the duration of hypoesthesia recovery.

: To investigate the in vivo musculoaponeurotic architecture of the masseter muscle (MM) volumetrically, in asymptomatic participants with ultrasound. It was hypothesized that the mean fiber bundle length (FBL) and mean aponeurotic height of laminae of MM differ significantly between the relaxed state and maximally contracted state upon elevation of the mandible.

Pemphigus vegetans is a rare variant of pemphigus vulgaris. Here, we report a rare case of post-parturition pemphigus vegetans in a young woman without any prior medical history. The patient presented with extensive oral mucosal erosion, conjunctivitis, and fingernail dystrophy. A histopathological biopsy taken from the tongue showed pseudoepitheliomatous hyperplasia of the epidermis with eosinophilic spongiosis, and an intraepidermal cleft and direct immunofluorescence showed intercellular IgG and C3 deposition.

This study aimed to investigate the expression of phosphofructose kinase-2/fructose-2, 6-biophosphatase 3 (PFKFB3) and its association with lymphangiogenesis in oral squamous cell carcinoma (OSCC).

To quote Benjamin Franklin “an ounce of prevention is better than a pound of cure”. Of course, historians would be correct in stating that this famous quote was in reference to a fire prevention speech given in his city of Philadelphia, however the statement could not be more applicable to disease prevention. Vaccine-preventable diseases are a significant cause of morbidity and mortality. Furthermore, the trickle-down effects, of any such disease cannot be measured just in the specific patient mortality or disease sequelae.

The coronavirus disease (COVID-19) pandemic increased anxiety among general population. The purpose of this project was to investigate attitudes and anxiety among Oral and Maxillofacial Surgery (OMS) residents during the early COVID-19 pandemic.

This study aimed to explore the characteristics and prognoses of primary jaw malignancies and identify valuable prognostic factors.

: Current pediatric temporomandibular joint (TMJ) reconstruction options are limited. The aim of this project was to develop a proof-of-principle porcine model for a load bearing, customized 3-dimensional (3D) printed and bone morphogenic protein 2 (BMP2)-coated scaffold implanted in a pedicled (temporal) flap as a regenerative approach to pediatric TMJ mandibular condyle reconstruction.

The aim of this study was to determine the effect of omega-3 on the painful symptomatology of osteoarthritis (OA) in synovial joints,

This systematic review aims to describe the value of saliva as a noninvasive sample for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in comparison with the current method for sample collection, the nasopharyngeal swab.

It is a little more than 125 years since Wilhelm Conrad Röntgen discovered X-rays, with clinical applications commencing within months. 1 Although the diagnostic benefits were easily appreciated, the carcinogenic potential of low dose X-ray examinations was not for a long time.2 X-ray exposures can be divided into high dose, such as radiotherapy, fluoroscopy and low dose diagnostic radiology. Once a patient receives more than approximately 2 Grays (Gy) of absorbed dose to the skin, erythema can be seen.

We read the recent article1 that describes a series of 8 cases of oral manifestations of coronavirus disease 2019 (COVID-19) and its management with great interest. In case 1, photobiomodulation was applied as an adjunct for symptomatic relief of oral lesions. We would like to throw light on the viral load reduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by photoactivation of the photosensitizer (PS) using a specific wavelength through peroxidation that could expand the scope of photodynamic therapy (PDT) in health care during this pandemic.

We thank Professors Joseph and Prasanth for their comments in their letter to the Editor entitled “Is photodynamic therapy (PDT) a viable antiviral weapon against COVID-19 in Dentistry?”

A 43-year-old-male with no medical conditions presented to his dentist with a left maxillary swelling present for 1 year. His physical exam revealed a 2-cm × 2-cm, poorly demarcated, firm mass in the left anterior maxilla causing mobility of the associated teeth. He had a bluish discoloration of the anterior maxillary mucosa. A computed tomographic scan demonstrated a homogeneous and uniformly radiolucent, well-defined mass in the left anterior maxilla primarily involving the alveolus and the roots of teeth 7-12.

Our objective was to investigate the molecular etiology of osteogenesis imperfecta type VIII and dental anomalies in four siblings of a Karen tribe family.

Carcinoma with dual neuroendocrine and non-neuroendocrine components are recognized albeit as a rare occurrence among the head and neck tumours. Owing to a disjointed pathology taxonomy and a lack of defining criteria, these tumours have remained under-recognized and poorly understood by pathologists and oncologists. Herein, we present a heretofore unreported case of a mixed neuroendocrine non-neuroendocrine carcinoma occurring as a carcinoma ex-pleomorphic adenoma (CXPA) in the soft palate of a 32-year-old man.

: This systematic review (SR) aimed to evaluate the epidemiologic profile, screen for possible risk factors and evaluate the spectrum of clinical characteristics of oral squamous cell carcinoma (OSCC) around dental implants (DI).

The aim of this study was to compare the diagnostic performance of convolutional neural networks (CNNs) with the performance of human observers for the detection of simulated periapical lesions on periapical radiographs.

This study aimed to evaluate changes in mandibular trabecular bone structure in bruxism using fractal analysis on digital panoramic radiographs obtained with automatic dosing.

During oral pathology daily practice, true amyloid may be identified in oral amyloidosis and several odontogenic tumors. However, histological examination often reveals other oral and perioral diseases with similar eosinophilic, acellular, amorphous substances. These include extensive areas of collagenous sclerosis, fibrin deposition, elastic fiber degeneration and dentinoid material, which may resemble amyloid under light microscopic examination. These materials are often termed amyloid-like due to their close histological resemblance to true amyloid.

Innovation in modern medicine never ceases to amaze me. During my days as an oral medicine fellow at the National Institutes of Dental Research in the late 1980s, where salivary gland dysfunction was studied from various approaches, I was introduced to the concept of salivary gland transplantation. More accurately, this was the transfer of a major gland out of the planned field of head and neck radiation therapy in an attempt to preserve gland function. This gland transfer would hopefully facilitate oral health maintenance and future ability to partake in gastronomic pleasures for the cancer survivor.

: To curb opioid over-prescription and diversion, 49 states implemented mandatory Prescription Drug Monitoring Programs (PDMPs). This study aims to examine the changes in analgesic prescription patterns associated with mandatory PDMP usage by oral and maxillofacial surgeons.

To evaluate the dimensional changes of alveolar bone and soft tissue after dental extraction/post-extraction in alveoli filled/grafted with collagen (Collacone®) compared to those left empty/ungrafted.

The objective of this study was to assess the duration of effect of a single dose of Biotène Moisturizing Spray on xerostomia compared to water spray.

Limited data is currently available regarding outcomes following transoral robotic surgery (TORS) in the salvage setting. This study aims to investigate the functional and oncological outcomes following TORS in salvage oropharyngeal tumours.

The objective of this study was to compare the diagnostic performance of magnetic resonance imaging (MRI) and computed tomography (CT) in differentiating pleomorphic adenomas from Warthin tumors using radiomics.

Dentists must be vigilant in the search for signs and symptoms of oral cancer in their patients. Failure to recognize these features can be serious; however, the low prevalence of oral cancer makes this encounter infrequent for most dentists.1 Because the average annual incidence of oral cancer in the United States is estimated to be 12 per 100,000 population,2 every dentist is open to the probability of encountering patients with this disease.

Carotid body tumors (CBT) are benign but challenging. This study compared of outcome three techniques of the surgical treatment of CBTs.

The objective of this study was to assess inflammatory cytologic alterations in the oral epithelium of patients on human immunodeficiency virus pre-exposure prophylaxis (PrEP).

The objective of this study was to determine correlations between magnetic resonance imaging (MRI) features including radiologic depth of invasion (r-DOI) and pathologic DOI (p-DOI) of squamous cell carcinoma of the buccal mucosa.

: Identification of the transcription factor binding sites (TFBS) in the promoter of HOX genes and elucidation of the comprehensive interaction of transcription factors (TFs)/genes with HOX.

The calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasm that makes up less than 1% of all odontogenic tumors. This study aims to describe a case series of CEOT spanning 25 years and to review, and compare our results with, the existing literature.

: The objective of the present study was to analyse the functional results of TMJ range i.e. Trismus index, Lateral excursion, Protrusion, Retrusion, Occlusion, Masticatory efficiency, Re-establishment of anatomic relationship of TMJ, Aesthetics to improve the quality of life and catalogue its complications in terms of ramus shortening on affected side, deviation, facial asymmetry, neurological deficit and reankylosis.

Dentinogenesis imperfecta (DI) requires dental treatment. This study investigated the characteristics of DI teeth associated with osteogenesis imperfecta (OI) and COL1A2 mutations.

Several surgical techniques can be performed to achieve setback of the mandible. The bilateral sagittal split osteotomy (BSSO) is most frequently used, but vertical ramus osteotomies performed through extra- or intraoral access can achieve the same sagittal and occlusal relations1,2. The disadvantage of the BSSO is a relative high ratio of neurosensory disturbance (NSD), ranging from 10-20% in most studies3. Also, surgical site infection (SSI) can be encountered, and may require additional surgery for removal of osteosynthesis-material4.

Face transplantation (FT) is performed for patients with severe facial disfigurements due to trauma caused by burns, ballistic injuries or animal attacks, or severe congenital or attained malformations. The goal of the FT is to restore missing or injured facial structures, improve quality of life (QOL), and enhance functional abilities, such as chewing, swallowing, breathing, talking, and esthetics.1 The first FT was performed in 2005.2-4 Currently, the estimated global number of FTs is 44, performed in 17 different centers.