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- Biological information and functional analysis reveal the role of discoidin domain receptor 1 in oral squamous cell carcinomaby Xilei Zhu, Mianfeng Yao, Bihan Zhang, Chao Zhu, Feiya Zhu, Ting Shen, Changyun Fang on 22/10/2020 at 12:00 am
: This study aimed to establish a framework of the role of DDR1 in OSCC through biological data and functional analysis.
- Letter to the Editor: Enhancing the predictive potential pre-operative DOI assessment using imaging techniquesby Gargi Sarode, Sachin C Sarode, Namrata Sengupta, Shankargouda Patil on 22/10/2020 at 12:00 am
Haraguchi et al.1 in a recently published paper compared pre-operative depth of invasion (DOI) obtained with magnetic resonance imaging (MRI) and histological DOI to predict the cervical lymph node metastasis (CLNM) of tongue squamous cell carcinoma. The threshold value for DOI in determining CLNM was also proposed. We take this opportunity to communicate our perspective on further enhancing the predictive potential pre-operative DOI assessment using imaging techniques.
- The Blue Palate – A Case-Series of Imatinib-Related Oral Pigmentation and Literature Reviewby Christopher C. Donnell, Richard L. Walton, Marco Carrozzo on 18/10/2020 at 12:00 am
Pigmented oral mucosal lesions are diverse and differential diagnosis can range from benign conditions such as oral melanotic macule to malignancies such as oral malignant melanoma. Imatinib mesylate is a tyrosine-kinase inhibitor used as a first-line medication in the management of oncohaematological conditions such as chronic myeloid leukaemia and gastrointestinal stromal tumours. Side effects of Imatinib therapy are common, and paradoxically Imatinib has been associated with both hypo- and hyperpigmented lesions, the underlying mechanism for which is still unclear.
- Novel oral biomarkers predicting oral malodorby Yu Takaesu, Nao Suzuki, Marie Naito, Takeshi Watanabe, Atsushi Shimazu, Naoko Yatabe, Masahiro Yoneda, Takao Hirofuji, Takashi Hanioka on 17/10/2020 at 12:00 am
We sought new markers to predict oral malodor.
- Is There a Role of Toothpastes in The Development of Recurrent Aphthous Stomatitis? A Prospective Controlled Clinical Trial with Skin Patch Testingby Kaya Ozden Hatice, Ayse Adin Selcuk on 16/10/2020 at 12:00 am
Oral mucosa is exposed to a large number of antigenic agents contained in toothpastes. These agents are reported to stimulate recurrent aphthous stomatitis (RAS) pathogenesis, and toothpastes that do not contain probable allergenic substances reduced the number and frequency of aphthous ulcers. We aimed to determine whether the skin patch test (SPT) can be used to determine toothpaste allergens playing role in the etiology of RAS.
- A rare case of a metastatic giant cell-rich osteosarcoma of the mandible: update and differential diagnostic considerationsby Lucas Alves da Mota Santana, Fernanda Aragão Felix, José Alcides Almeida de Arruda, Leorik Pereira da Silva, Érika de Abreu Costa Brito, Wilton Mitsunari Takeshita, Cleverson Luciano Trento on 16/10/2020 at 12:00 am
A metastatic giant cell-rich osteosarcoma to the jaws is an exceedingly rare neoplasm. To date, less than 10 cases have been reported in the English language literature. In this article, we describe an additional case of a metastatic giant cell-rich osteosarcoma that demonstrated the diagnostic challenge of a painless mass in the posterior mandible of a 19-year-old girl who exhibited rapid and aggressive local growth. The lesion was confirmed radiologically as an ill-defined expansive osteolytic mass showing cortical perforation.
- “Ossifying” Mucoepidermoid Carcinoma: A Deceptive Clinical Presentationby Brian Wolf, Stephen Roth, John Fantasia, Victor Nannini on 16/10/2020 at 12:00 am
Mucoepidermoid carcinoma is the most common salivary gland malignancy, accounting for 27% of all salivary gland cancers. Identified in 1921 and first analyzed in 1945, mucoepidermoid carcinoma has demonstrated a widely diverse histology with several morphologic variants having been described. One rare feature is the formation of intratumoral bone, which has been previously reported once in the English language literature. While the etiology of these calcifications is still not known, it is believed that this finding is independent of overall disease prognosis.
- Prognostic factors in mucoepidermoid carcinoma of the minor salivary glands: A single-center retrospective studyby Masahiko Terauchi, Yasuyuki Michi, Hideaki Hirai, Kentaro Sugiyama, Akane Wada, Hiroyuki Harada, Tetsuya Yoda on 16/10/2020 at 12:00 am
To investigate the prognostic effects of clinical and histological findings in patients with mucoepidermoid carcinoma (MEC) of minor salivary glands.
- Expression of transmembrane protein Aquaporin- 3 in oral epithelial dysplasia and oral squamous cell carcinomaby Dr. M.S. Lekshmy, Dr. T.T. Sivakumar, Dr. Anna P. Joseph, Dr. B.R. Varun, Dr. Vinod Mony, Dr. A. Reshmi on 16/10/2020 at 12:00 am
To evaluate Aquaporin-3 (AQP3) expression in patient samples of oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC), thereby assessing the potential of AQP3 as a molecular marker for tumour progression.
- Diatoms: a novel cause of granulomatous inflammation of the head and neckby Thabet AlHousami, Ivan J Stojanov, Padraig Deighan, Daniel D. Rhoads, Devaki Sundararajan, Jeremy Lassetter, Yuri Shamritsky, Sadru Kabani, Vikki Noonan on 16/10/2020 at 12:00 am
We report the first four cases of intraoral non-necrotizing granulomatous foreign body reactions to diatoms, plausibly as a result of exogenous material introduced following iatrogenic or traumatic injury.
- Effect of image acquisition parameters on the radiopacity of bulk-fill and nanocomposite resinsby Mariah Scotti Alérico, Francine Kühl Panzarella, Fabiana Mantovani Gomes França, Carlos Augusto de Souza Lima, José Luiz Cintra Junqueira, Ricardo Raitz on 15/10/2020 at 12:00 am
: This study evaluated the radiopacity of 2 bulk-fill resins (SonicFill and Filtek Bulk Fill) and a nanocomposite (Filtek Z350 XT) resin compared with enamel, dentin, and aluminum as measured with different exposure parameters.
- Osteonecrosis of the jaw associated with Imatinib therapy in myeloproliferative neoplasm - A rare case report.by Lokendra Gupta, Kanchan Dholam, Yogesh Janghel, Sandeep V. Gurav on 15/10/2020 at 12:00 am
Medication related osteonecrosis of the jaw (MRONJ) is a relatively infrequent nevertheless a very well-known adverse effect of bisphosphonates. This rare complication of bisphosphonates is rarest with the usage of certain drugs. Tyrosine kinase inhibitors (TKIs), particularly used in renal cell carcinoma or gastrointestinal tumors as a chemotherapeutic agent, can precipitate this particular medical condition of bone when it is associated either with radiation or bisphosphonates, though, mono-drug therapy with TKIs rarely causes MRONJ.
- Analysis of The Oral Cavity: Portal to Health and Disease, a massive open online course in oral medicineby Katherine France, Uri Hangorsky, Chia-Wei Wu, Thomas P. Sollecito, Eric T. Stoopler on 14/10/2020 at 12:00 am
The aims of this study were to (1) analyze the demographic characteristics of learners participating in The Oral Cavity: Portal to Health and Disease (TOC), the first massive open online course in oral medicine, and (2) assess worldwide interest in accessible, high-quality oral medicine education.
- Relationship of psychological factors with salivary flow rate and cortisol levels in individuals with oral lichen planus: a case-control studyby Alessandra Laís Pinho Valente Pires, Juliana Araújo da Silva Simoura, Joana Dourado Martins Cerqueira, Ynara Bosco de Oliveira Lima-Arsati, Franco Arsati, Jean Nunes dos Santos, Valéria Souza Freitas on 11/10/2020 at 12:00 am
To analyze the relationship of psychological factors with salivary flow rate and cortisol levels in individuals with oral lichen planus.
- An innovative PantoDict program for reporting panoramic radiographs using automatic speech recognition in dental education: a randomized observer-blinded studyby A. Bock, D. Elvers, E. Goloborodko, C. Kramer, K. Kniha, F. Hölzle, C. Spreckelsen, A. Modabber on 10/10/2020 at 12:00 am
To assess the effect of an e-learning program including automatic speech recognition on outcomes assessment in interpreting panoramic radiographs at a dental school.
- Inevitable change: the “new normal”by Kevin L. Rieck on 09/10/2020 at 12:00 am
A year ago I wrote an editorial about personal wellness in the setting of caring for patients. Shortly after that publication, the world changed considerably due to the coronavirus disease 2019 (COVID-19) global pandemic. As I write this, there are over 30 million reported cases, and we are approaching nearly one million deaths worldwide. This has affected all of us in multiple ways and will continue to do so for the foreseeable future. We are social beings, and the impact of quarantine has been extremely difficult.
- Value of multilevel sectioning of labial salivary gland biopsies in the diagnosis of Sjögren's syndromeby Simon Kold Bredahl, Jesper Reibel, Anne Marie Lynge Pedersen on 08/10/2020 at 12:00 am
To examine the diagnostic value of cutting labial salivary gland (LSG) biopsies at two levels in the histological evaluation for Sjögren's syndrome (SS).
- Painful palatal lesion in a 90-year-old femaleby Daria Vasilyeva, Kevin C. Lee, Garrick Alex, Scott M. Peters on 05/10/2020 at 12:00 am
A 90-year-old female presented to a local oral and maxillofacial surgeon for evaluation of a painful lesion involving her left palatal mucosa. The patient first reported discomfort involving the left side of her mouth approximately 2 days before her presentation. Her medical history was significant for dementia, so it was unclear if this acute presentation was accurate or if the lesion had been present for longer than the reported time. The patient's home health aide did state that she noticed an appreciable decrease in the patient's ability to eat and drink over the past 24 hours before her appointment.
- When should sleep bruxism be considered in the diagnosis of temporomandibular disorders?by Yu Chen Chien, Davor Seferovic, Julian N. Holland, Muhammad F. Walji, Shawn S. Adibi on 05/10/2020 at 12:00 am
Both temporomandibular disorders (TMDs) and sleep bruxism (SB) are known to be destructive to the masticatory system. However, the association between the 2 conditions is poorly understood. The aim of our study was to assess the relationship between TMD and SB through the signs and symptoms in 2 patient groups: TMD only and TMD with SB.
- Survival Outcomes following Modern Multidisciplinary Management of Oral Squamous Cell Carcinoma in Australiaby Timothy P.J. Liu, Bradley M. Fisher, Benjamin Chua, Jonathan R. Clark, Tsu-Hui (Hubert) Low, Martin D. Batstone on 05/10/2020 at 12:00 am
Oral squamous cell carcinoma (SCC) has been traditionally described as a highly lethal disease. This study aims to provide updated multi-institutional data on the survival of oral SCC patients in Australia.
- Evaluation of streak metal artifacts in cone beam computed tomography by using the Gumbel distribution: a phantom studyby Yoshikazu Nomura, Hiroshi Watanabe, Nisha Gowri Manila, Sakurako Asai, Tohru Kurabayashi on 02/10/2020 at 12:00 am
The aim of this study was to confirm whether streak metal artifacts (SMAs) between titanium implants on cone beam computed tomography (CBCT) images could be evaluated by using the Gumbel distribution (GD). Moreover, the influence of different scan settings on SMAs was investigated.
- A large pedunculated nodule in the tongue in a 52-year-old maleby Junho Jung, Jongseok Shin, Joo-Young Ohe on 02/10/2020 at 12:00 am
A 52-year-old male who was physically well-developed and well-nourished presented to the oral and maxillofacial department at Kyung Hee University Medical Center (Seoul, Republic of Korea) with a slow-growing exophytic mass. The patient could not recall when he first noticed the mass. The mass was asymptomatic and located in the anterior dorsum of the tongue; it was described as movable, nontender, nonulcerated, and smooth (Figure 1). T1–weighted magnetic resonance imaging (MRI) was performed to examine the extent of the lesion, and it revealed a 5.7 × 3.4 mm, noninvasive, pedunculated, isolated soft tissue mass (Figure 2).
- Hereditary angioedema: report of the dental treatment of 12 Brazilian patientsby Bernardo Correia Lima, Claudia de S. Thiago Ragon, Rafaela Alves Veras, Alessandra Oliveira Ferrari Gomes, Maria Luiza Oliva Alonso, Solange Oliveira Rodrigues Valle, Sandra Regina Torres, Michelle Agostini on 01/10/2020 at 12:00 am
The aim of this study was to report on clinical experience in Brazil in the dental treatment and the oral conditions of a group of patients with hereditary angioedema (HAE).
- Table of Contentson 01/10/2020 at 12:00 am
- Editorial Boardon 01/10/2020 at 12:00 am
- Society Pageon 01/10/2020 at 12:00 am
- Information for Readerson 01/10/2020 at 12:00 am
- Plasma Cell Mucositis related to Qat chewing: a report of two cases and review of the literatureby Artysha Tailor, Michael N. Pemberton, Dr. Ruth Murphy, Dr. Anne M. Hegarty on 29/09/2020 at 12:00 am
Plasma cell mucositis is a rare, benign mucosal condition with a hallmark histological appearance of a dense polyclonal plasma cell infiltrate. A variety of mucosal sites can be affected and its presentation varies from warty or cobblestone appearance to an intensely erythematous, lobulated appearanceIdiopathic cases of plasma cell mucositis have been well documented in the literature and attempts have been made to link the condition with underlying hypersensitivity reactions however reports have shown many inconsistencies.
- Can local anesthesia with ropivacaine provide postoperative analgesia in impacted mandibular third molars extraction? A randomized clinical trialby Klinger de Souza Amorim, Anne Caroline Gercina, Filipe Mazar Santos Ramiro, Leonardo de Araújo Medeiros, Jaiza Samara Macena de Araújo, Francisco Carlos Groppo, Liane Maciel de Almeida Souza on 29/09/2020 at 12:00 am
The aim of this study was to compare the local anesthesia efficacy of ropivacaine 0.75% compared to lidocaine 2% with 1:100,000 epinephrine for postoperative analgesia following extraction of impacted mandibular third molar.
- An incidental finding of a radiolucent lesion in the mandibular condyleby Somdipto Das, William C. Faquin, Paul A. Caruso, Joseph P. McCain, Meredith August , Leonard B. Kaban on 28/09/2020 at 12:00 am
A 13-year old boy was referred to the senior author (LBK) for evaluation of a radiolucent lesion in the left mandibular condyle demonstrated on a diagnostic panoramic radiograph. The patient was in his usual state of good health, waiting to begin orthodontic treatment, when this asymptomatic finding was observed.
- Diffusion-weighted magnetic resonance imaging of the oral and maxillofacial region: optimal fat suppression methodby Hiroaki Shimamoto, Minami Majima, Hideki Kitamori, Tomomi Tsujimoto, Naoya Kakimoto, Yuri Iwamoto, Yurie Senda, Sven Kreiborg, Sanjay M. Mallya, Shumei Murakami on 28/09/2020 at 12:00 am
To compare 3 fat suppression methods—water excitation (WE), chemical shift selective (CHESS), and short T1 inversion recovery (STIR)—for optimal image quality and apparent diffusion coefficient (ADC) values with magnetic resonance imaging (MRI) using diffusion-weighted imaging (DWI) of the oral and maxillofacial region.
- Important Radiographic Features in the Identification of Osseous Dysplasia-Related Osteomyelitisby Chen Nadler, Susanne E. Perschbacher, Daniel Septon, Ragda Abdalla-Aslan, Michael Pharoah, Linda Lee on 27/09/2020 at 12:00 am
The aims of this study were to identify radiographic features that distinguish osseous dysplasia-related osteomyelitis (OD-related OM) from OD without OM and to detect possible causes of OD-related OM.
- Regulatory T-cell expansion in oral and maxillofacial Langerhans cell histiocytosisby Chuhan Zhang, Jingyi Gao, Jianghai He, Chundong Liu, Xiaozhi Lv, Xuemin Yin, Yongjian Deng, Zhiyun Lu, Zhihui Tian on 26/09/2020 at 12:00 am
Langerhans cell histiocytosis (LCH) is a rare myeloid-origin neoplasm characterized by the expansion and dissemination of CD1 a+/CD207+ dendritic cells (LCH cells), but the rarity of its occurrence has long impeded progress in understanding its pathology. We focus on the potentially important role that regulatory T cells (T-reg) play in the oral and maxillofacial LCH tumor microenvironment (TME).
- Pixel gray measurement for the diagnosis of dental ankylosis in cone beam computed tomography imagesby Inara Carneiro Costa Rege, Tessa de Lucena Botelho, Allisson Filipe Lopes Martins, Cláudio Rodrigues Leles, Elismauro Francisco Mendonça on 26/09/2020 at 12:00 am
The aim of this study was to investigate dental ankylosis in unerupted or partially erupted teeth by using cone beam computed tomography (CBCT) to quantify pixel intensity.
- Central odontogenic fibroma: an international multicentric study of 62 casesby Ana Luiza Oliveira Corrêa Roza, Emanuel Mendes Sousa, Amanda Almeida Leite, Gleyson Kleber Amaral-Silva, Thayná Melo de Lima Morais, Vivian Petersen Wagner, Lauren Frenzel Schuch, Ana Carolina Uchoa Vasconcelos, José Alcides Almeida de Arruda, Ricardo Alves Mesquita, Felipe Paiva Fonseca, Aline Corrêa Abrahão, Michelle Agostini, Bruno Augusto Benevenuto de Andrade, Ericka Janine Dantas da Silveira, René Martínez-Flores, Benjamin Martínez Rondanelli, Javier Alberdi-Navarro, Liam Robinson, Constanza Marin, José Narciso Rosa Assunção Júnior, Renato Valiati, Eduardo Rodrigues Fregnani, Alan Roger Santos-Silva, Marcio Ajudarte Lopes, Keith D. Hunter, Syed Ali Khurram, Paul M. Speight, Adalberto Mosqueda-Taylor, Willie F.P. van Heerden, Román Carlos, John M. Wright, Oslei Paes de Almeida, Mário José Romañach, Pablo Agustin Vargas on 26/09/2020 at 12:00 am
The aim of this study was to report the clinicopathologic features of 62 cases of central odontogenic fibroma (COdF).
- Prognosis for the impacted lower third molars: panoramic reconstruction versus tomographic imagesby Paulo Eliezer de Oliveira Moreira, David Normando, Lucas Rodrigues Pinheiro, Gustavo Antônio Martins Brandão on 25/09/2020 at 12:00 am
The aim of this cross-sectional accuracy study was to compare panoramic reconstruction (PR) and multiplanar reconstruction (MPR) images, which are used to establish the prognosis for impacted mandibular third molars in relation to professional decision making.
- A randomized prospective comparison of maxillomandibular fixation (MMF) techniques: “SMARTLock” hybrid MMF versus MMF screwsby Nawaf Aslam-Pervez, John F. Caccamese, Gary Warburton on 25/09/2020 at 12:00 am
The aim of this study was to assess the efficacy of the “SMARTLock” hybrid system and determine whether it results in fewer intraoperative and postoperative complications compared with placement of intermaxillary fixation (IMF) screws in trauma patients.
- Optimizing telemedicine encounters for oral and maxillofacial surgeons during the COVID-19 pandemicby Hwi Sean Moon, Tim T. Wang, Karthik Rajasekaran, Ryan Brewster, Rabie M. Shanti, Neeraj Panchal on 25/09/2020 at 12:00 am
The coronavirus disease 2019 (COVID-19) pandemic has changed conventional patterns of medical practice across all health disciplines, including oral and maxillofacial surgery. The use of telemedicine has rapidly expanded to uphold safety strategies of physical distancing and disease transmission reduction while maintaining uninterrupted care of patients. To date, there are no specific guidelines to optimize telemedicine encounters in oral and maxillofacial surgery. The goal of this article is to provide best practices for both oral and maxillofacial surgeons and their patients to effectively use telemedicine for the duration of the COVID-19 pandemic and beyond.
- Single nucleotide polymorphisms and serologic levels of hypoxia-inducible factor1 α and vascular endothelial growth factor are associated with increased risk of oral submucous fibrosis in gutka users among a North Indian populationby Shalini R. Gupta, Alpana Sharma, Nidhi Gupta, Kalaivani Mani on 25/09/2020 at 12:00 am
Tissue hypoxia in oral submucous fibrosis (OSMF) induces hypoxia-inducible factor (HIF)-1 α and vascular endothelial growth factor (VEGF), causing angiogenesis. Single nucleotide polymorphisms (SNPs) may predict susceptibility to environmental carcinogens and to development of OSMF, as well as its severity and malignant transformation. This study aimed to determine the serologic levels and frequencies of SNPs of HIF-1 α and VEGF in OSMF.
- Primordial odontogenic tumor: report of 2 new casesby Wilson A. Delgado-Azañero, Oslei Paes de Almeida, Alessandro Antônio Costa Pereira, Carine Ervolino de Oliveira, Márcio Américo Dias, Gustavo Florez-Valderrama, Thayna Melo de Lima Morais, Bruno Augusto Linhares Almeida Mariz, Adalberto Mosqueda-Taylor on 25/09/2020 at 12:00 am
Primordial odontogenic tumor (POT) is a recently described benign odontogenic tumor, with only 16 cases reported in the literature. We present 2 new cases of POT affecting the mandible. Case 1 is that of 12-year-old girl with an asymptomatic, slow-growing mass, causing facial asymmetry. Radiography showed a well-defined unilocular radiolucency surrounding an impacted second premolar. Case 2 is that of a 13-year-old girl with a mass involving the crown of the unerupted third molar and showing similar radiographic features.
- Oxidative–protective effect of nuclear receptor coactivator 7 on arecoline-induced endothelial-to-mesenchymal transitionby Yuan Wang, Di Luo, Xun Yuan, Yin Luo, Xiufeng Cheng, Yijun Gao, Xiaoyan Xie on 25/09/2020 at 12:00 am
Overproduction of reactive oxygen species (ROS) has been implicated in inflammatory activities and tumorigenesis in oral submucous fibrosis (OSF). Nuclear receptor coactivator 7 (NCOA7) is capable of regulating cellular responses to ROS. The aim of this study was to investigate the expression of NCOA7 in endothelial cells and the role of NCOA7 in areca nut–induced endothelial-to-mesenchymal transition (EndMT).
- Salivary gland neoplasms: A 10-year review of a major referral center in Ghanaby Grace E. Parkins, Paa-Kwesi Blankson, Albert Affum, Matthew Owusu Boamah, Josephine Sackeyfio on 25/09/2020 at 12:00 am
The aim of this study was to describe the clinicopathologic features of salivary gland tumors (SGTs) that were managed at a major referral center in Ghana.
- A survey assessing the early effects of COVID-19 pandemic on oral and maxillofacial surgery training programsby Branden Brar, Mohamed Bayoumy, Andrew Salama, Andrew Henry, Radhika Chigurupati on 25/09/2020 at 12:00 am
The coronavirus disease 2019 (COVID-19) pandemic has specific implications for oral and maxillofacial surgeons because of an increased risk of exposure to the virus during surgical procedures involving the aerodigestive tract. The objective of this survey was to evaluate how the COVID-19 pandemic affected oral and maxillofacial surgery (OMFS) training programs during the early phase of the pandemic.
- Diffuse-type tenosynovial giant cell tumor of the temporomandibular joint with skull base invasion: a report of 22 cases with literature reviewby Ying Liu, Bao-hua Fan, Yi-ran Tan, Dong-wang Zhu, Min-jun Dong, Li-zhen Wang, Jiang Li, Jian Sun, Chen-ping Zhang, Tong Ji, Wen-jun Yang, Ahmed Abdelrehem, Yi-qun Wu, Lai-ping Zhong on 25/09/2020 at 12:00 am
The aim of this study was to retrospectively analyze the clinical characteristics, surgical treatment, and prognosis of patients with diffuse-type tenosynovial giant cell tumor (D-TGCT) involving the temporomandibular joint (TMJ) and the skull base.
- The influence of articular eminence morphology on temporomandibular joint anterior dislocationsby Adir Cohen, Mati Cohen Sela, Natanel Shooraki, Michael Alterman, Nardy Casap on 25/09/2020 at 12:00 am
The aim of this study was to investigate the correlation between the bony morphology of the articular eminence and the occurrence of idiopathic anterior temporomandibular joint (TMJ) dislocation.
- Hereditary gingival fibromatosis associated with the missense mutation of the KCNK4 geneby Pierluigi Mariani, Khrystyna Zhurakivska, Rossella Santoro, Gregorio Laino, Diana Russo, Luigi Laino on 25/09/2020 at 12:00 am
Hereditary gingival fibromatosis (HGF) is a rare oral condition that may appear as an isolated entity or as part of a genetic disease or syndrome. Molecular and biochemical mechanisms that trigger this pathologic process are not completely understood. In this article, we present a rare case of hereditary gingival fibromatosis in conjunction with a syndromic phenotype, associated with a rare missense mutation of the KCNK4 gene. This mutation induces a change in the structure of the TRAAK channel belonging to the 2-pore potassium channels.
- Are pathogenic BRCA1 mutations associated with parotid mucoepidermoid carcinoma? A case reportby Paulo Goberlânio de Barros Silva, Rosane Oliveira de Sant'ana, Clarissa Gondim Picanço-Albuquerque, Isabelle Joyce de Lima Silva-Fernandes, Maria Júlia Barbosa Bezerra, Maria Claudia dos Santos Luciano, Marcos Venício Alves Lima on 25/09/2020 at 12:00 am
To describe a patient with BRCA1 mutation, mucoepidermoid parotid, multiple breasts, and thyroid cancers.
- Prevalence of p16 expression in oropharyngeal squamous cell carcinoma in southern Brazilby Fábio Muradás Girardi, Vivian P. Wagner, Manoela Domingues Martins, Aliende Lengler Abentroth, Luiz Alberto Hauth on 25/09/2020 at 12:00 am
Our aim was to evaluate the prevalence of human papillomavirus (HPV)–positive tumors in a cohort of patients with oropharyngeal squamous cell carcinoma (OPSCC) at a single center in southern Brazil and determine the short-term prognostic factors in this sample.
- Nodular lesion on the posterior dorsal surface of the tongueby Evânio Vilela Silva, Maria Leticia de Almeida Lança, Heitor Albergoni Silveira, Andreia Bufalino, Cláudia Maria Navarro, Alfredo Ribeiro-Silva, Jorge Esquiche León, Luciana Yamamoto de Almeida on 25/09/2020 at 12:00 am
A 47-year-old man was referred to the Oral Medicine Service of our institution complaining of discomfort during eating and speaking because of the presence of a painless nodule on the posterior dorsal surface of the tongue. The patient had noticed the tongue lesion 1 month ago, and it had gradually expanded until it reached the size seen in the current clinical presentation. The medical history was noncontributory. Intraoral examination revealed a pink, pedunculated, exophytic, well-defined nodule, with a discretely lobulated and substantial ulcerated surface covered by a yellowish pseudomembrane without any tendency to bleed; measuring approximately 2 cm in greatest diameter; and located on the posterior dorsal region of the tongue (Figure 1).
- Diagnostic accuracy of colposcopic examination in patients with oral dysplastic lesionsby Sarah Ahmed Mohamed Mahmoud, Mohsen Kazem Abdul Latif, Heba Mahmoud Dahmoush, Eman Aly Hussein on 24/09/2020 at 12:00 am
Colposcopy is a direct microscopic method and is the gold standard tool to detect early cervical dysplastic lesions. In the past, many attempts have been made to use gynecologic methods to examine the oral mucosa. The aim of this study was to detect the diagnostic accuracy of oral colposcopy in diagnosing oral dysplastic lesions in comparison with microscopic evaluation based on biopsy and compare Reid's Colposcopic Index (RCI) and the Swede scoring system in diagnosing oral dysplastic lesions.
- Μενού Περιοδικών
- The New England Journal of Medicine
- Journal of Oral and Maxillofacial Surgery
- International Journal of Oral and Maxillofacial Surgery
- Journal of Cranio-Maxillofacial Surgery
- British Journal of Oral and Maxillofacial Surgery
- Oral and Maxillofacial Surgery (DGMKG)
- Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
- Oral and Maxillofacial Surgery Clinics
- Oral Oncology
- Clinical Oral Implants Research
- Otolaryngology — Head and Neck Surgery
- Implant Dentistry
- Head & Neck
- American Journal of Orthodontics and Dentofacial Orthopedics